Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052169 | 0.88 | TSHR (0.44) | ALDH1A1TSHRLMNA | |
| SCHEMBL27383637 | 0.85 | TSHR (0.51) | ALDH1A1TSHRDAOMAPT | |
| SCHEMBL28052882 | 0.84 | CES2 (0.45) | ALDH1A1TSHR | |
| SCHEMBL12063879 | 0.84 | KDM5A (0.46) | TSHRNR4A2 | |
| SCHEMBL27734240 | 0.84 | TSHR (0.44) | ALDH1A1TSHRALOX15MAPTMEN1 | |
| SCHEMBL28855166 | 0.84 | NR4A2 (0.55) | ALDH1A1TSHRNR4A2MRGPRX4SRD5A2 | |
| SCHEMBL11687234 | 0.84 | RXRA (0.45) | TSHRAKR1C3MRGPRX4SRD5A2MEN1 | |
| SCHEMBL23040963 | 0.84 | RXRA (0.51) | ALDH1A1NR4A2AKR1C3MRGPRX4MEN1 | |
| SCHEMBL28119542 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15MAPTNR4A2 | |
| SCHEMBL6387117 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNADAOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105407888-A | Novel bicyclic bromodomain inhibitors | ZENITH EPIGENETICS CORP | 2016-03-16 | — | — | CN | claimed |
| CN-105407888-A | Novel bicyclic bromodomain inhibitors | ZENITH EPIGENETICS CORP | 2016-03-16 | — | — | CN | disclosed |