SCHEMBL28855192

SCHEMBL28855192

OB(O)Oc1c(F)cccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 11/20 0.40
SLC6A2 P23975 11/20 0.40
GAA P10253 2/20 0.39
SLC6A4 P31645 4/20 0.38
TAAR1 Q96RJ0 1/20 0.37
KMT2A Q03164 1/20 0.36
SLC6A3 Q01959 3/20 0.36
LPAR1 Q92633 1/20 0.35
LPAR5 Q9H1C0 1/20 0.35
BACE1 P56817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL615196 0.85 CES2 (0.37) HTR1ASLC6A2SLC6A4KMT2ASLC6A3
SCHEMBL31079469 0.85 KMT2A (0.42) KMT2A
SCHEMBL28991603 0.85 HTR1A (0.38) HTR1ASLC6A2GAASLC6A4TAAR1
SCHEMBL29922740 0.83 HTR1A (0.39) HTR1ASLC6A2GAASLC6A4TAAR1
SCHEMBL29112996 0.81 HTR1A (0.38) HTR1ASLC6A2GAASLC6A4TAAR1
SCHEMBL23272973 0.78 CA2 (0.36)
SCHEMBL30547988 0.78 TSHR (0.46) KMT2A
SCHEMBL29263394 0.76 CA1 (0.35)
SCHEMBL31096182 0.76 HTT (0.33)
SCHEMBL28401102 0.76 KDM4E (0.34) HTR1ASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422674-B Organic molecules, in particular for optoelectronic devices 三星显示有限公司 2024-03-22 CN disclosed
CN-115551867-B Fused tricyclic compounds, pharmaceutical compositions and uses thereof 劲方医药科技(上海)有限公司 2024-02-20 CN disclosed
CN-117242059-A Heterocyclic compound and organic light-emitting element comprising same LT素材株式会社 2023-12-15 CN disclosed
CN-112334474-B Compound and organic light emitting device comprising the same 株式会社LG化学 2023-07-21 CN disclosed
CN-116425682-A Pyrimidine-1 (2H) -oxo compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2023-07-14 CN disclosed
CN-110818641-B Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology 北京诺诚健华医药科技有限公司 2022-10-14 CN disclosed