Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868181 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL27856197 | 0.82 | ALDH1A1 (0.38) | MAPTALDH1A1LMNAHSD17B10CYP2D6 | |
| SCHEMBL27973284 | 0.82 | CA1 (0.34) | MAPTSMN1; SMN2TSHR | |
| SCHEMBL7337554 | 0.79 | MAPT (0.44) | MAPTALDH1A1LMNAHSD17B10CYP2D6 | |
| SCHEMBL27588334 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAHSD17B10CYP2D6 | |
| SCHEMBL6755582 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL8149342 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL27631184 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CYP2D6CYP2C19 | |
| SCHEMBL2858639 | 0.79 | CPB2 (0.43) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL15429377 | 0.78 | MAPT (0.43) | MAPTALDH1A1LMNAHSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-A | biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2018-01-09 | — | — | CN | disclosed |