SCHEMBL8149342

SCHEMBL8149342

CCCC(Cl)C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 2/20 0.40
ALOX15 P16050 2/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
HDAC7 Q8WUI4 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
CHRM1 P11229 1/20 0.37
AKR1A1 P14550 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27631184 1.00 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10POLBALOX15
SCHEMBL2868181 0.90 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10POLBALOX15
SCHEMBL10853428 0.88 HDAC7 (0.39) ALDH1A1LMNAHSD17B10SOAT1HDAC7
SCHEMBL8155883 0.86 CA2 (0.44) ALDH1A1LMNAHSD17B10POLBTDP1
SCHEMBL21811945 0.86 HDAC7 (0.38) ALDH1A1HDAC7HDAC8HDAC6HDAC9
SCHEMBL2858639 0.86 CPB2 (0.43) ALDH1A1LMNAHSD17B10POLBALOX15
SCHEMBL6755582 0.86 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10POLBALOX15
SCHEMBL15743811 0.85 ZDHHC7 (0.44) TSHRCPB2
SCHEMBL11359669 0.84 HDAC7 (0.38) ALDH1A1LMNAHDAC7HDAC8HDAC6
SCHEMBL6560711 0.84 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10POLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440123-A Synthetic method of 4,5, 6-trichloropyrimidine 南京普锐达医药科技有限公司 2020-07-24 CN claimed
CN-103910741-A Bisbenzylisoquinoline betaine as well as preparation method thereof and application thereof in preparation of anti-tumor medicament UNIV SHANDONG NORMAL 2014-07-09 CN claimed
CN-103910738-A Bisbenzylisoquinoline quaternary ammonium salt as well as preparation method and application thereof in preparing antitumor drug UNIV SHANDONG NORMAL 2014-07-09 CN claimed
CN-118271599-A Polyamide composition for automotive interior parts and preparation method thereof 四川光亚新材料科技有限公司 2024-07-02 CN disclosed
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
CN-113166036-B Photopolymerizing sensitizers with migration resistance 川崎化成工业株式会社 2023-10-10 CN disclosed
CN-115916774-A Process for the preparation of fluoxastrobin and intermediates thereof UPL有限公司 2023-04-04 CN disclosed
CN-115916774-A Process for the preparation of fluoxastrobin and intermediates thereof UPL有限公司 2023-04-04 CN disclosed
CN-115490641-A Synthesis method of 2-methyl-4, 5, 6-trichloropyrimidine 大连大学 2022-12-20 CN disclosed
CN-109311821-B 6-hydroxy-5- (phenyl/heteroarylsulfonyl) pyrimidin-4 (1H) -ones as APJ agonists 百时美施贵宝公司 2022-10-14 CN disclosed
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER KAWASAKI KASEI CHEMICALS LTD. (JP) 2022-04-07 US disclosed
WO-2020054116-A1 PHOTOPOLYMERIZATION SENSITIZER 川崎化成工業株式会社 2020-03-19 WO disclosed
WO-2020054874-A1 PHOTOPOLYMERIZATION SENSITIZER 川崎化成工業株式会社 2020-03-19 WO disclosed
CN-103910738-A Bisbenzylisoquinoline quaternary ammonium salt as well as preparation method and application thereof in preparing antitumor drug UNIV SHANDONG NORMAL 2014-07-09 CN disclosed
CN-100395264-C Novel method for the synthesis of perindopril and its pharmaceutically acceptable salts SERVIER LAB (FR) 2008-06-18 CN disclosed
CN-1839147-A Method for synthesis of perindopril and its pharmaceutically acceptable salts SERVIER LAB (FR) 2006-09-27 CN disclosed
CN-1489560-A Preparation of fluorine compounds 2004-04-14 CN disclosed
US-6041157-A Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same GOETZ FREDERICK JAMES (US) 2000-03-21 US disclosed
US-4254262-A IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-03 US disclosed
US-4234744-A Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides DEUTSCHE GOLD- UND SILBER SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA ALDH1A1 838/4885LMNA 54/4885HSD17B10 130/4885
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER F12, F10, PCNA ALDH1A1 838/4885LMNA 54/4885HSD17B10 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.