Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 12/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.40 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953406 | 0.85 | PIK3CD (0.38) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL16712832 | 0.76 | CA2 (0.45) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL6933510 | 0.75 | NOS3 (0.56) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL29899421 | 0.75 | NOS3 (0.56) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL29498290 | 0.74 | CA2 (0.43) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL84522 | 0.73 | PIK3CD (0.40) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL12327194 | 0.72 | NOS3 (0.58) | MTORPIK3CAPIK3R1PIK3CBNOS3 | |
| SCHEMBL12110247 | 0.72 | PIK3CA (0.39) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL29435509 | 0.72 | PIK3CA (0.39) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 | |
| SCHEMBL22583123 | 0.71 | GABRP (0.39) | MTORPIK3CAPIK3CDPIK3C2BPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-107652270-A | 2‑（4 morpholinyls）4,6 disubstituted pyrimidines/s-triazine compound and its salt and application | 西安交通大学 | 2018-02-02 | — | — | CN | disclosed |