Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.56 |
| ▸ | HTR3A known ✓ | P46098 | 1/20 | 0.56 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542780 | 0.97 | L3MBTL1 (0.59) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| Cyclohexane SCHEMBL27743405 | 0.97 | L3MBTL1 (0.59) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| SCHEMBL2312380 | 0.97 | L3MBTL1 (0.59) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| SCHEMBL93630 | 0.97 | L3MBTL1 (0.59) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| Benzene SCHEMBL28818227 | 0.97 | L3MBTL1 (0.59) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| SCHEMBL1968506 | 0.97 | L3MBTL1 (0.59) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| SCHEMBL28105340 | 0.97 | L3MBTL1 (0.59) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| Hydrochloric Acid SCHEMBL9291151 | 0.95 | ALDH1A1 (0.60) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| Water SCHEMBL10922019 | 0.95 | L3MBTL1 (0.57) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E | |
| Hydrochloric Acid SCHEMBL5417163 | 0.95 | ALDH1A1 (0.60) | L3MBTL1MBTD1L3MBTL3LMNAHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110151854-A | Rush digestion composition, preparation method and application containing longan total phenol extract | 嘉兴市爵拓科技有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-107803225-A | It is a kind of to be used to produce ruthenium catalyst of vinyl chloride and preparation method thereof | 浙江工业大学 | 2018-03-16 | — | — | CN | claimed |
| CN-107744836-A | A kind of preparation method and applications of load-type ion liquid catalyst | 浙江工业大学 | 2018-03-02 | — | — | CN | claimed |
| CN-109155444-A | Electrolyte for rechargeable electrochemical cells | EOS能源储存有限责任公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108586306-A | A method of lutein and zeaxanthin are detached using ionic liquid strengthening extraction | 华东理工大学 | 2018-09-28 | — | — | CN | disclosed |