Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896802 | 0.92 | SMN1; SMN2 (0.37) | PPOXPPARASLC22A12TP53ALDH1A1 | |
| SCHEMBL28856550 | 0.92 | SMN1; SMN2 (0.37) | PPOXPPARASLC22A12TP53ALDH1A1 | |
| SCHEMBL28856515 | 0.86 | SLC22A12 (0.43) | SLC22A12TP53ALDH1A1PRNP | |
| SCHEMBL28856481 | 0.86 | PPARA (0.48) | PPARASLC22A12MEN1KMT2ARXFP1 | |
| SCHEMBL28856556 | 0.84 | ALDH1A1 (0.36) | PPOXPPARASLC22A12TP53ALDH1A1 | |
| SCHEMBL29896764 | 0.84 | ALDH1A1 (0.36) | PPOXPPARASLC22A12TP53ALDH1A1 | |
| SCHEMBL29896755 | 0.83 | AAK1 (0.39) | PPOXPPARAMEN1KMT2APOLB | |
| SCHEMBL28856498 | 0.83 | AAK1 (0.39) | PPOXPPARAMEN1KMT2APOLB | |
| SCHEMBL29896717 | 0.80 | SLC22A12 (0.36) | PPOXPPARASLC22A12 | |
| SCHEMBL28856494 | 0.80 | SLC22A12 (0.36) | PPOXPPARASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |