Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856536 | 0.94 | CYP1A2 (0.35) | CYP1A2TSHRCYP2C19MAPTPKM | |
| SCHEMBL28856495 | 0.90 | ALOX5AP (0.34) | CYP1A2TSHRCYP2C19MAPTPKM | |
| SCHEMBL28856521 | 0.84 | SLC22A12 (0.33) | CYP1A2CYP2C19SLC22A12 | |
| SCHEMBL28856479 | 0.83 | MAPT (0.34) | CYP1A2TSHRCYP2C19MAPTPKM | |
| SCHEMBL28856544 | 0.82 | MAPT (0.34) | CYP1A2TSHRCYP2C19MAPTPKM | |
| SCHEMBL28856511 | 0.81 | CA1 (0.35) | CYP1A2TSHRCYP2C19MAPTPKM | |
| SCHEMBL28856504 | 0.80 | SLC22A12 (0.33) | CYP1A2CYP2C19SLC22A12 | |
| SCHEMBL28856526 | 0.80 | MAPT (0.32) | CYP1A2TSHRCYP2C19MAPTPKM | |
| SCHEMBL28856542 | 0.79 | ALDH1A1 (0.37) | MAPTALDH1A1SLC22A12 | |
| SCHEMBL28856493 | 0.78 | SLC22A12 (0.38) | PKMKDM4EL3MBTL1ALDH1A1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |