Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 12/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856516 | 0.93 | KDM4E (0.33) | SLC22A12CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28856521 | 0.93 | SLC22A12 (0.33) | SLC22A12AKR1C3AKR1C1CYP1A2CYP2D6 | |
| SCHEMBL28955000 | 0.85 | HPGD (0.34) | SLC22A12CYP1A2 | |
| SCHEMBL28856553 | 0.85 | SLC22A12 (0.31) | SLC22A12HTR6 | |
| SCHEMBL28856536 | 0.84 | CYP1A2 (0.35) | SLC22A12CYP1A2CYP2C19 | |
| SCHEMBL28856487 | 0.83 | GRM2 (0.31) | GRM2GRM3 | |
| SCHEMBL28856517 | 0.82 | SLC22A12 (0.43) | SLC22A12 | |
| SCHEMBL28856551 | 0.82 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL28856502 | 0.80 | CYP1A2 (0.35) | SLC22A12CYP1A2CYP2C19 | |
| SCHEMBL28856496 | 0.80 | CA12 (0.39) | SLC22A12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |