Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856558 | 0.85 | SLC22A12 (0.49) | SLC22A12 | |
| SCHEMBL28856519 | 0.85 | SLC22A12 (0.38) | SLC22A12PRF1ALDH1A1HPGDTP53 | |
| SCHEMBL28856529 | 0.84 | TP53 (0.33) | SLC22A12KDM4EL3MBTL1PRF1ALDH1A1 | |
| SCHEMBL28856520 | 0.83 | SLC22A12 (0.39) | SLC22A12KDM4EL3MBTL1PKMALDH1A1 | |
| SCHEMBL28856560 | 0.81 | ALDH1A1 (0.33) | SLC22A12KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL28856524 | 0.80 | SLC22A12 (0.44) | SLC22A12 | |
| SCHEMBL28856515 | 0.78 | SLC22A12 (0.43) | SLC22A12ALDH1A1TP53 | |
| SCHEMBL28856502 | 0.78 | CYP1A2 (0.35) | SLC22A12KDM4EL3MBTL1PKMALDH1A1 | |
| SCHEMBL28856536 | 0.78 | CYP1A2 (0.35) | SLC22A12KDM4EL3MBTL1PKMALDH1A1 | |
| SCHEMBL28856495 | 0.77 | ALOX5AP (0.34) | KDM4EL3MBTL1PKMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |