Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856501 | 0.94 | SLC22A12 (0.35) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28856483 | 0.82 | SMN1; SMN2 (0.34) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28954999 | 0.78 | SLC22A12 (0.34) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28856514 | 0.77 | ALDH1A1 (0.37) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MAPT | |
| SCHEMBL29896737 | 0.77 | ALDH1A1 (0.37) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MAPT | |
| SCHEMBL28856485 | 0.76 | SLC22A12 (0.35) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28856554 | 0.76 | SLC18A2 (0.35) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL28856503 | 0.75 | MAPK1 (0.34) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28856557 | 0.74 | SLC22A12 (0.34) | ALDH1A1SLC22A12SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28856484 | 0.72 | MAPT (0.40) | KDM4EMAPTGAANPSR1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |