Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichlorobenzene SCHEMBL27912052 | 0.86 | TSHR (0.55) | TSHRALDH1A1LMNAKDM4EHSD11B1 | |
| Bromobenzene SCHEMBL27368728 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1LMNACYP1A2CYP2D6 | |
| Alcohol SCHEMBL27794091 | 0.77 | LMNA (0.41) | TSHRALDH1A1LMNAHSD11B1CYP1A2 | |
| 1,2-Dichlorobenzene SCHEMBL28076107 | 0.77 | TSHR (0.52) | TSHRALDH1A1LMNAKDM4ECYP1A2 | |
| Ethylamine SCHEMBL28129404 | 0.77 | PNMT (0.44) | TSHRALDH1A1LMNAHSD11B1CYP1A2 | |
| Bromobenzene SCHEMBL28846383 | 0.76 | ALDH1A1 (0.48) | TSHRALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL29637350 | 0.76 | — | — | |
| SCHEMBL251393 | 0.76 | — | — | |
| Chlorobenzene SCHEMBL27411248 | 0.75 | TSHR (0.52) | TSHRALDH1A1CYP1A2TDP1HTT | |
| Naphthalene SCHEMBL27264348 | 0.74 | TSHR (0.57) | TSHRALDH1A1LMNAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |