Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 10/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 10/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 10/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857052 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2POLBHTT | |
| SCHEMBL28928304 | 0.82 | ATM (0.37) | ALDH1A1LMNASMN1; SMN2POLBTPSAB1 | |
| Hydrochloric Acid SCHEMBL9836812 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2POLBTPSAB1 | |
| SCHEMBL29179866 | 0.79 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2POLBHTT | |
| SCHEMBL28523191 | 0.77 | ATM (0.42) | ALDH1A1SMN1; SMN2POLBHTTTPSAB1 | |
| SCHEMBL29260116 | 0.77 | TPSAB1 (0.39) | ALDH1A1LMNASMN1; SMN2POLBTPSAB1 | |
| SCHEMBL29260114 | 0.77 | TPSAB1 (0.39) | ALDH1A1LMNASMN1; SMN2POLBTPSAB1 | |
| SCHEMBL22387906 | 0.77 | MEN1 (0.40) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28857104 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2POLBHTT | |
| SCHEMBL23145119 | 0.76 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151561-A | Targeted autophagy conjugates and methods | 前沿药品公司 | 2022-10-04 | — | — | CN | disclosed |