Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 12/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 12/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 12/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29179866 | 0.94 | ALDH1A1 (0.55) | ALDH1A1LMNATPSAB1TPSD1TPSG1 | |
| SCHEMBL28857047 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNATPSAB1TPSD1TPSG1 | |
| SCHEMBL29013169 | 0.81 | TPSAB1 (0.43) | ALDH1A1TPSAB1TPSD1TPSG1SMN1; SMN2 | |
| SCHEMBL29144075 | 0.78 | TPSAB1 (0.44) | ALDH1A1TPSAB1TPSD1TPSG1SMN1; SMN2 | |
| SCHEMBL28425908 | 0.77 | EPHX2 (0.45) | ALDH1A1TPSAB1TPSD1TPSG1 | |
| Hydrochloric Acid SCHEMBL9833904 | 0.76 | TPSAB1 (0.38) | ALDH1A1LMNATPSAB1TPSD1TPSG1 | |
| SCHEMBL29260222 | 0.76 | TPSAB1 (0.44) | ALDH1A1TPSAB1TPSD1TPSG1POLB | |
| Hydrochloric Acid SCHEMBL9836812 | 0.75 | ALDH1A1 (0.38) | ALDH1A1LMNATPSAB1TPSD1TPSG1 | |
| SCHEMBL29144108 | 0.74 | KMT2A (0.50) | ALDH1A1TPSAB1TPSD1TPSG1POLB | |
| SCHEMBL27668592 | 0.74 | TPSAB1 (0.42) | ALDH1A1LMNATPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151561-A | Targeted autophagy conjugates and methods | 前沿药品公司 | 2022-10-04 | — | — | CN | disclosed |