SCHEMBL28857424

SCHEMBL28857424

CO[Si](CNC(=O)n1ccnc1)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.35
GAA P10253 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TBXAS1 P24557 2/20 0.33
MAPT P10636 2/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.32
AHR P35869 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17726997 0.83 ALDH1A1 (0.41) GAAALDH1A1MAPTTSHR
SCHEMBL6808774 0.78 KMT2A (0.41) HTTALDH1A1MAPTAHRKMT2A
SCHEMBL7724075 0.77 BCHE (0.40) GAAALDH1A1MAPTTSHRKDM4E
SCHEMBL7146803 0.76 KMT2A (0.43) HTTGAAALDH1A1MAPTKMT2A
SCHEMBL11121639 0.76 L3MBTL1 (0.36) ALDH1A1MAPT
SCHEMBL18034386 0.76 ALDH1A1 (0.38) GAAALDH1A1MAPTTSHR
SCHEMBL17285650 0.75 ALDH1A1 (0.35) HTTALDH1A1TBXAS1MAPT
SCHEMBL5257422 0.75 QPCT (0.45) GAAALDH1A1AHRNPSR1KMT2A
SCHEMBL31469851 0.73 ALDH1A1 (0.34) ALDH1A1TBXAS1MAPT
SCHEMBL17512612 0.73 CYP19A1 (0.36) ALDH1A1TBXAS1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105358563-B Azoles silane compound, surface treatment liquid, surface treatment method and its utilization 四国化成工业株式会社 2018-03-30 CN disclosed