Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857604 | 0.88 | LMNA (0.72) | LMNAPOLBDHODHMAPTSMN1; SMN2 | |
| SCHEMBL28857591 | 0.88 | HIF1A (0.60) | LMNAPOLBHIF1AEPAS1MAPT | |
| SCHEMBL28857605 | 0.88 | HIF1A (0.60) | LMNAPOLBHIF1AEPAS1MAPT | |
| SCHEMBL28955070 | 0.80 | LMNA (0.64) | LMNAPOLBDHODHMAPTSMN1; SMN2 | |
| SCHEMBL28857646 | 0.79 | LMNA (1.00) | LMNAPOLBHIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL28857580 | 0.77 | LMNA (0.66) | LMNAPOLBHIF1AEPAS1DHODH | |
| SCHEMBL28857626 | 0.76 | PTGDR2 (0.58) | LMNAPOLBMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL25154861 | 0.76 | HIF1A (0.64) | LMNAPOLBHIF1AEPAS1MAPT | |
| SCHEMBL27715515 | 0.76 | HTT (0.56) | LMNAPOLBHIF1AEPAS1MAPT | |
| SCHEMBL28857612 | 0.75 | GAA (0.57) | LMNAPOLBMAPTSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |