Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719617 | 0.89 | L3MBTL1 (0.41) | CYP2C19L3MBTL1CYP2D6SRCPOLB | |
| SCHEMBL19480805 | 0.86 | ESR1 (0.40) | CYP2C19L3MBTL1SRCPOLBLMNA | |
| SCHEMBL17733788 | 0.84 | PTGS1 (0.51) | CYP2C19SMN1; SMN2L3MBTL1CYP2D6LMNA | |
| SCHEMBL13065909 | 0.77 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2CYP2D6SRCPOLB | |
| SCHEMBL13460409 | 0.77 | L3MBTL1 (0.43) | L3MBTL1AURKARPS6KB1GAAGPR88 | |
| Phosphoric Acid SCHEMBL29027087 | 0.76 | ACP3 (0.44) | L3MBTL1CYP2D6SRCAURKARPS6KB1 | |
| SCHEMBL15382015 | 0.76 | LMNA (0.47) | L3MBTL1LMNAGAA | |
| SCHEMBL15382014 | 0.76 | LMNA (0.47) | L3MBTL1LMNAGAA | |
| SCHEMBL16746745 | 0.76 | LMNA (0.47) | L3MBTL1LMNAGAA | |
| SCHEMBL15994823 | 0.75 | GPR88 (0.51) | SMN1; SMN2L3MBTL1LMNAAURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107743484-A | The amphyl for the treatment of cancer | 麦地那创新药物研究中心基金会 | 2018-02-27 | — | — | CN | disclosed |