Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL1807174 | 0.91 | MEN1 (0.66) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL29935522 | 0.91 | MEN1 (0.65) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL378581 | 0.91 | MEN1 (0.65) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL2525493 | 0.89 | MEN1 (0.63) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| Toluene SCHEMBL28209101 | 0.83 | RXRA (0.55) | HTTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10441909 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL23296145 | 0.81 | RXRA (0.58) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL23758511 | 0.81 | CYP1A2 (0.67) | MEN1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL30235602 | 0.81 | MEN1 (0.66) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10900761 | 0.81 | MEN1 (0.66) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330630-B | Benzofuran compounds and its preparation method and application | 上海交通大学 | 2018-04-17 | — | — | CN | disclosed |