SCHEMBL28858397

SCHEMBL28858397

O=C1CC=CC1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
GAA P10253 2/20 0.38
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
HTR2B P41595 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
GFER P55789 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RECQL P46063 1/20 0.34
CACNA1D Q01668 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1943626 0.79 CYP2C19 (0.37) MAPTGAALMNATP53CYP1A2
SCHEMBL28810923 0.72 CYP19A1 (0.36) LMNAMAPK1ALDH1A1HSD17B10SMN1; SMN2
SCHEMBL30832182 0.72 CYP2C19 (0.42) MAPTGAACFTRGOPCCYP3A4
SCHEMBL29089150 0.69 DDB1 (0.37) MAPTGAACFTRGOPCLMNA
SCHEMBL30832166 0.69 SMN1; SMN2 (0.36) LMNACYP1A2HPGDRECQLSMN1; SMN2
SCHEMBL30832176 0.69 LMNA (0.38) MAPTLMNAALDH1A1KMT2ASMN1; SMN2
SCHEMBL30832160 0.69 LMNA (0.38) MAPTLMNAALDH1A1KMT2ASMN1; SMN2
SCHEMBL10475181 0.68 CFTR (0.47) MAPTGAACFTRGOPCLMNA
SCHEMBL11060271 0.67 MAPT (0.44) MAPTGAACFTRGOPCLMNA
SCHEMBL15657030 0.64 KMT2A (0.52) MAPTGAACFTRGOPCLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107923128-A Thin sheet paper 花王株式会社 2018-04-17 CN disclosed