Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832176 | 0.83 | LMNA (0.38) | SMN1; SMN2LMNANPSR1MAOAMAOB | |
| SCHEMBL30832160 | 0.83 | LMNA (0.38) | SMN1; SMN2LMNANPSR1MAOAMAOB | |
| SCHEMBL30832183 | 0.78 | GRM2 (0.39) | LMNACYP1A2CYP2C9CYP2C19GRM2 | |
| SCHEMBL30832186 | 0.76 | GRM2 (0.41) | LMNAGRM2 | |
| SCHEMBL5170700 | 0.75 | HDAC8 (0.38) | CYP2C19GRM2HDAC8DDB1CRBN | |
| SCHEMBL30832182 | 0.74 | CYP2C19 (0.42) | SMN1; SMN2CYP2C19DDB1CRBNTSHR | |
| SCHEMBL30832177 | 0.69 | MEN1 (0.32) | NPSR1 | |
| SCHEMBL28858397 | 0.69 | MAPT (0.38) | SMN1; SMN2LMNACYP1A2RECQLNPSR1 | |
| SCHEMBL30832188 | 0.68 | KDM1A (0.33) | KDM1A | |
| SCHEMBL30832169 | 0.68 | SLC6A3 (0.37) | SMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865878-A | Chiral indoline-3-one derivative and preparation method thereof | 郑州大学 | 2024-04-12 | — | — | CN | disclosed |