Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729212 | 0.63 | CYP19A1 (0.36) | CYP19A1ALDH1A1POLBSMN1; SMN2PKM | |
| SCHEMBL3438177 | 0.62 | CYP19A1 (0.41) | CYP19A1ALDH1A1POLBSMN1; SMN2ADORA2B | |
| SCHEMBL7559919 | 0.62 | MAPT (0.53) | CYP19A1ALDH1A1POLBSMN1; SMN2PKM | |
| SCHEMBL4827312 | 0.62 | ESR2 (0.50) | CYP19A1ALDH1A1POLBSMN1; SMN2PKM | |
| Formaldehyde SCHEMBL27083167 | 0.61 | HCAR2 (0.40) | CYP19A1ALDH1A1POLBSMN1; SMN2PKM | |
| SCHEMBL7627234 | 0.61 | CYP19A1 (0.34) | CYP19A1ALDH1A1POLBSMN1; SMN2PKM | |
| SCHEMBL27706109 | 0.61 | ALDH1A1 (0.38) | CYP19A1ALDH1A1POLBSMN1; SMN2PKM | |
| SCHEMBL11428571 | 0.59 | PKM (0.55) | ALDH1A1PKMADORA2B | |
| SCHEMBL18304588 | 0.59 | ADORA2B (0.32) | ADORA2B | |
| SCHEMBL9330401 | 0.59 | MAPK1 (0.37) | CYP19A1ALDH1A1POLBSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739566-B | Containing the chirality five-membered of sulphonamide and ring framework compound and preparation method and purposes | Third Military Medical University, Chinese People's Liberation Army (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103739566-A | Chiral five-membered bi-heterocyclic skeleton compound containing sulfamide, preparation method and application | UNIV PLA 3RD MILITARY MEDICAL | 2014-04-23 | — | — | CN | disclosed |