SCHEMBL28858401

SCHEMBL28858401

CCCCc1cccc(N(N)c2ccc(CN)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.41
LPL P06858 2/20 0.39
LIPG Q9Y5X9 2/20 0.39
HTR2A P28223 2/20 0.38
TLR8 Q9NR97 2/20 0.37
AOC3 Q16853 1/20 0.37
DRD2 P14416 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
SLC6A4 P31645 1/20 0.36
HTR1A P08908 1/20 0.36
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28858466 0.95 HTR2A (0.40) SKP2HTR2ATLR8AOC3SLC6A2
SCHEMBL28210771 0.80 TLR8 (0.37) SKP2LPLLIPGHTR2ATLR8
SCHEMBL920929 0.78 LPL (0.49) SKP2LPLLIPGHTR2ATLR8
SCHEMBL13142802 0.78 TAAR1 (0.40) AOC3DRD2
SCHEMBL28210774 0.77 TLR8 (0.41) TLR8AOC3
SCHEMBL28210210 0.77 SIGMAR1 (0.49)
SCHEMBL10356301 0.75 LPL (0.46) SKP2LPLLIPG
SCHEMBL394855 0.74 HTR2A (0.61) SKP2LPLLIPGHTR2ASLC6A2
SCHEMBL22786464 0.74 TAAR1 (0.52) HTR2AAOC3SLC6A2SLC6A4HTR1A
SCHEMBL15743670 0.74 LPL (0.49) LPLLIPGAOC3DRD2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985464-B Solid catalytic component for olefin polymerization and catalyst thereof 中国石油天然气股份有限公司 2018-04-03 CN claimed