Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 5/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13142794 | 0.87 | SIGMAR1 (0.47) | CYP2C19SIGMAR1TP53 | |
| SCHEMBL24478732 | 0.85 | CYP2C19 (0.42) | TAAR1CYP2C19CNR2NOS1NOS2 | |
| SCHEMBL21392007 | 0.85 | CYP2C19 (0.42) | TAAR1CYP2C19CNR2NOS1NOS2 | |
| SCHEMBL28858401 | 0.78 | SKP2 (0.41) | AOC3DRD2 | |
| SCHEMBL12374362 | 0.75 | LPL (0.45) | TAAR1CYP2C19CNR2DRD2DRD3 | |
| SCHEMBL14997333 | 0.75 | LPL (0.45) | TAAR1CYP2C19CNR2DRD2DRD3 | |
| SCHEMBL21391970 | 0.74 | LPL (0.51) | — | |
| SCHEMBL9844594 | 0.74 | FFAR1 (0.41) | CYP2C19CNR2AOC3 | |
| SCHEMBL28858466 | 0.74 | HTR2A (0.40) | NOS1NOS2AOC3DRD1DRD3 | |
| SCHEMBL12619659 | 0.74 | CYP2C19 (0.36) | CYP2C19SIGMAR1CNR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7794907-B2 | Hydrazone compound, electrophotographic photoreceptor comprising the hydrazone compound, and image forming apparatus equipped with the electrophotographic photoreceptor | SHARP KABUSHIKI KAISHA (JP) | 2010-09-14 | — | — | US | disclosed |