Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164925 | 0.84 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL28152366 | 0.76 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL28821689 | 0.76 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL29208946 | 0.75 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL81412 | 0.75 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL27541003 | 0.75 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL3338971 | 0.74 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL28874767 | 0.74 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL28175772 | 0.73 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL9422121 | 0.72 | THRB (0.45) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922379-A | Substituted guanidine derivatives | 宇部兴产株式会社 | 2018-04-17 | — | — | CN | disclosed |