SCHEMBL9422121

SCHEMBL9422121

C=CC(=O)OCCC[SiH](Cc1ccccc1)OCC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.45
TSHR P16473 6/20 0.44
HPGD P15428 1/20 0.44
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 2/20 0.41
HCAR2 Q8TDS4 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
AKR1B10 O60218 4/20 0.36
AKR1B1 P15121 4/20 0.36
LMNA P02545 1/20 0.35
ALOX5 P09917 1/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 1/20 0.34
THRA P10827 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7161579 0.87 THRB (0.47) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL3305049 0.82 TDP1 (0.45) THRBTSHRALDH1A1CYP3A4MAPK1
SCHEMBL27986809 0.82 THRB (0.45) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL5164925 0.82 TSHR (0.59) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL27986822 0.77 THRB (0.47) THRBTSHRHPGDALDH1A1CYP3A4
Diphenylmethane SCHEMBL28294258 0.74 TSHR (0.67) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL28108282 0.74 TSHR (0.43) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL28821689 0.74 TSHR (0.57) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL81412 0.73 TSHR (0.59) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL146669 0.73 THRB (0.63) THRBTSHRHPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476964-B Polymeric binder layer as a ceramic precursor 3M创新有限公司 2022-04-26 CN disclosed
US-20220119692-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2022-04-21 US disclosed
US-11292940-B2 Polymeric adhesive layers as ceramic precursors 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
US-11285702-B2 Siloxane-based adhesive layers as ceramic precursors 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-03-29 US disclosed
CN-109642143-B Siloxane-based adhesive layer as a ceramic precursor 3M创新有限公司 2021-09-24 CN disclosed
US-10947396-B2 Curable antifouling composition, method of use, and articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-03-16 US disclosed
US-20190352542-A1 POLYMERIC ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M INNOVATIVE PROPERTIES COMPANY 2019-11-21 US disclosed
US-20190300634-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2019-10-03 US disclosed
US-20190218425-A1 SILOXANE-BASED ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M INNOVATIVE PROPERTIES COMPANY 2019-07-18 US disclosed
EP-3487949-A1 SILOXANE-BASED ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M Innovative Properties Company (US) 2019-05-29 EP disclosed
WO-2018017554-A1 SILOXANE-BASED ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-01-25 WO disclosed
US-20160312040-A1 Curable Antifouling Composition, Method of Use, and Articles 3M INNOVATIVE PROPERTIES COMPANY 2016-10-27 US disclosed
EP-2920216-B1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2016-09-21 EP disclosed
EP-2920216-A1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M Innovative Properties Company (US) 2015-09-23 EP disclosed
WO-2014078195-A1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-22 WO disclosed
EP-2370536-B1 COATING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2013-11-06 EP disclosed
US-5284919-A Low temperature curing, waterproofing, acid resistance KANSAI PAINT COMPANY, LIMITED (JP) 1994-02-08 US disclosed
EP-0308203-A1 Curable composition KANSAI PAINT CO., LTD. (JP) 1989-03-22 EP disclosed