Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255317 | 0.84 | ALDH1A1 (0.47) | SLC6A4HTR2AKCNH2PPARGPPARA | |
| SCHEMBL18129370 | 0.81 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2PPARGPPARA | |
| SCHEMBL15707806 | 0.81 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2PPARGPPARA | |
| SCHEMBL10359812 | 0.81 | PPARG (0.46) | SLC6A4HTR2AKCNH2PPARGPPARA | |
| SCHEMBL11229520 | 0.78 | ALDH1A3 (0.41) | ALDH1A1 | |
| SCHEMBL24272296 | 0.78 | PPARG (0.44) | SLC6A4HTR2AKCNH2PPARGPPARA | |
| SCHEMBL1145316 | 0.77 | SLC6A4 (0.54) | SLC6A4HTR2AKCNH2KDM4EHSP90AA1 | |
| SCHEMBL29768449 | 0.77 | SLC6A4 (0.54) | SLC6A4HTR2AKCNH2KDM4EHSP90AA1 | |
| SCHEMBL9819014 | 0.76 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2PPARGPPARA | |
| SCHEMBL119603 | 0.76 | TDP1 (0.61) | HTR2APPARGPPARAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278914-B | A kind of synthesis technique of increase production of amines | 四川福思达生物技术开发有限责任公司 | 2018-04-13 | — | — | CN | disclosed |