SCHEMBL28858747

SCHEMBL28858747

O=C(O)c1ccc(-c2ccccc2O)cc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 6/20 0.58
MCL1 Q07820 5/20 0.58
HNF4A P41235 2/20 0.55
DHFR P00374 1/20 0.55
ALDH1A1 P00352 3/20 0.52
HPGD P15428 2/20 0.52
BCL2L1 Q07817 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PRKAB2 O43741 2/20 0.50
PRKAG1 P54619 2/20 0.50
PRKAA2 P54646 2/20 0.50
PRKAA1 Q13131 2/20 0.50
PRKAG3 Q9UGI9 2/20 0.50
PRKAG2 Q9UGJ0 2/20 0.50
PRKAB1 Q9Y478 2/20 0.50
DHODH Q02127 1/20 0.50
KDM4E B2RXH2 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9281315 0.88 ACMSD (0.56) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL28992674 0.86 KDM4E (0.56) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL28515959 0.85 PTPN1 (0.55) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL29369970 0.85 ALDH1A1 (0.56) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL14089922 0.84 ACMSD (0.62) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL13522879 0.84 KMT2A (0.65) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL10024265 0.84 MCL1 (0.67) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL8195032 0.83 KDM4E (0.56) ACMSDMCL1HNF4AALDH1A1HPGD
SCHEMBL17202660 0.81 MCL1 (0.77) ACMSDMCL1HNF4ADHFRALDH1A1
SCHEMBL6536000 0.80 MCL1 (0.54) ACMSDMCL1HNF4ADHFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104250214-B Polymerizable compounds and their use in liquid crystal displays 默克专利股份有限公司 2018-10-19 CN disclosed
CN-107973717-A Polymerizable compound and its purposes in a liquid crystal display 默克专利股份有限公司 2018-05-01 CN disclosed