SCHEMBL8195032

SCHEMBL8195032

O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.Oc1ccccc1-c1cc(-c2ccccc2O)cc(-c2ccccc2O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.56
HSD17B10 Q99714 3/20 0.53
CDC25A P30304 1/20 0.53
CDC25B P30305 1/20 0.53
POLB P06746 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
BCL2L1 Q07817 1/20 0.46
ACMSD Q8TDX5 3/20 0.45
TTR P02766 2/20 0.45
HNF4A P41235 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28992674 0.94 KDM4E (0.56) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL31517235 0.92 KDM4E (0.61) KDM4EHSD17B10CDC25ACDC25BPOLB
Catechol SCHEMBL9101540 0.86 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL28858747 0.83 ACMSD (0.58) KDM4EHSD17B10ALDH1A1HPGDBCL2L1
Salicylic Acid SCHEMBL9658512 0.83 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
Biphenyl SCHEMBL9102032 0.81 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
Phthalic Acid SCHEMBL20678581 0.80 CDC25B (0.77) KDM4EHSD17B10CDC25ACDC25BPOLB
Benzene SCHEMBL9407020 0.80 KDM4E (0.73) KDM4EHSD17B10CDC25ACDC25BPOLB
Pyrogallol SCHEMBL18591416 0.80 KDM4E (0.58) KDM4EHSD17B10CDC25ACDC25BPOLB
Phenol SCHEMBL30677823 0.79 POLB (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054031-A2 Increasing the molecular weight and modification of condensation polymers Ciba SC Holding AG (CH) 2000-11-22 EP disclosed