Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 16/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211515 | 0.83 | SLC6A4 (0.46) | SRPK1TSHRMAPT | |
| SCHEMBL28042824 | 0.78 | MAPT (0.39) | SRPK1TSHRLMNAALOX5APFEN1 | |
| SCHEMBL28179555 | 0.76 | CHRM4 (0.43) | SRPK1ALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL28242219 | 0.75 | CHRM4 (0.42) | SRPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL28227117 | 0.74 | CHRM4 (0.41) | SRPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL28227118 | 0.73 | CHRM4 (0.41) | SRPK1ALDH1A1TSHRLMNAKDM4E | |
| Tert-Butyl Formate SCHEMBL28042825 | 0.73 | NCF1 (0.45) | ALDH1A1ALOX5APFEN1MAPT | |
| SCHEMBL28129056 | 0.70 | MGLL (0.49) | SRPK1ALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL28227933 | 0.69 | SRPK1 (0.43) | SRPK1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL28849570 | 0.68 | MGLL (0.60) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461635-B | Phenylpiperazine derivatives and its application method and purposes | 乳源瑶族自治县大众药品贸易有限公司 | 2018-06-08 | — | — | CN | disclosed |