Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 7/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042821 | 0.83 | RXRA (0.46) | MAPTHTTMEN1TSHRKMT2A | |
| SCHEMBL28761804 | 0.79 | SLC6A9 (0.45) | MAPTHTTMEN1TSHRKMT2A | |
| SCHEMBL27648774 | 0.79 | PHGDH (0.46) | MAPTHTTMEN1TSHRKMT2A | |
| SCHEMBL28302825 | 0.78 | ALDH1A1 (0.53) | MAPTHTTMEN1TSHRKMT2A | |
| SCHEMBL28858764 | 0.78 | SRPK1 (0.42) | MAPTTSHRALOX5APFEN1SRPK1 | |
| Tert-Butyl Formate SCHEMBL28042825 | 0.75 | NCF1 (0.45) | MAPTALOX5APFEN1HTR2C | |
| SCHEMBL27981818 | 0.72 | CA12 (0.54) | MAPTHTTMEN1TSHRKMT2A | |
| SCHEMBL27793409 | 0.71 | POLB (0.47) | MAPTMEN1TSHRKMT2ALMNA | |
| SCHEMBL28001626 | 0.71 | MGLL (0.51) | MAPTHTTSMN1; SMN2 | |
| SCHEMBL27730809 | 0.69 | MAPT (0.46) | MAPTHTTMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461635-A | Phenylpiperazine derivatives, using method thereof and uses of the derivatives | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG MEDICINE TRADE CO LTD | 2016-04-06 | — | — | CN | disclosed |