Diaminooctane

Diaminooctane

SCHEMBL28858786

Cc1c(C(=O)O)cccc1C(=O)O.N.NC(N)CCCCCCCC(N)N.NCCCCCCCCN.NCCCCCCCN

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
HMGB1 P09429 1/20 0.39
GSR P00390 1/20 0.39
ALDH1A1 P00352 2/20 0.38
MYC P01106 1/20 0.37
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 2/20 0.37
DPP8 Q6V1X1 1/20 0.37
DPP9 Q86TI2 1/20 0.37
DPP7 Q9UHL4 1/20 0.37
NPC1 O15118 1/20 0.37
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
HPGD P15428 1/20 0.37
MMP2 P08253 1/20 0.36
CHRM1 P11229 1/20 0.36
FOLH1 Q04609 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diaminooctane SCHEMBL28161215 0.98 TSHR (0.40) TSHRHMGB1GSRALDH1A1MYC
SCHEMBL28857359 0.87 TSHR (0.47) TSHRHMGB1ALDH1A1MYCKDM4E
SCHEMBL28172624 0.87 TSHR (0.47) TSHRHMGB1ALDH1A1MYCKDM4E
SCHEMBL28170214 0.87 ALDH1A1 (0.51) TSHRALDH1A1KDM4E
Putrescine SCHEMBL28110610 0.83 TSHR (0.44) TSHRHMGB1ALDH1A1MYCKDM4E
Ammonia Solution, Strong SCHEMBL28842683 0.82 TSHR (0.41) TSHRHMGB1ALDH1A1MYCKDM4E
Octadecylamine SCHEMBL28210994 0.81 ALDH1A1 (0.44) TSHRHMGB1ALDH1A1
SCHEMBL28126374 0.81 ALDH1A1 (0.44) TSHRHMGB1ALDH1A1
Tetradecylamine SCHEMBL27874843 0.80 DNM1 (0.45) TSHRHMGB1ALDH1A1
Butane SCHEMBL28855255 0.80 ALDH1A1 (0.39) TSHRHMGB1ALDH1A1MYCKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104937010-B Polyamide, Preparation method and use 罗地亚经营管理公司 2018-04-27 CN disclosed