SCHEMBL28858809

SCHEMBL28858809

C1=CC=CNC=C1.COc1c(OC)c2cccc3c(OC)c(OC)c4cccc1c4c23

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MAPK1 P28482 1/20 0.43
POLB P06746 4/20 0.35
MAOA P21397 1/20 0.34
CTSV O60911 2/20 0.32
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
PRMT1 Q99873 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
MAPT P10636 2/20 0.30
HTT P42858 2/20 0.30
LMNA P02545 1/20 0.30
PABPC1 P11940 1/20 0.30
XBP1 P17861 1/20 0.30
NFKB1 P19838 1/20 0.30
SMARCA2 P51531 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28864503 0.72 ALDH1A1 (0.48) ALDH1A1KDM4ESMN1; SMN2MAPK1POLB
SCHEMBL28211259 0.72 MAPT (0.34) ALDH1A1KDM4ECYP1A2MAPTLMNA
Triphenylene SCHEMBL27642094 0.70 ALDH1A1 (0.36) ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1
SCHEMBL28436348 0.68 KDM4E (0.43) ALDH1A1KDM4ESMN1; SMN2MAPK1POLB
SCHEMBL28435330 0.67 CA1 (0.52) ALDH1A1KDM4ESMN1; SMN2MAPK1POLB
SCHEMBL10022717 0.66 ALDH1A1 (0.71) ALDH1A1KDM4ESMN1; SMN2MAPK1POLB
SCHEMBL28211263 0.66 KDM4E (0.34) ALDH1A1KDM4ESMN1; SMN2POLBMAOA
SCHEMBL21830457 0.65 KDM4E (0.44) ALDH1A1KDM4ESMN1; SMN2MAPK1POLB
SCHEMBL8859782 0.65 ALDH1A1 (0.82) ALDH1A1KDM4ESMN1; SMN2MAPK1POLB
SCHEMBL757747 0.65 KDM4E (0.82) ALDH1A1KDM4ESMN1; SMN2MAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104704661-B Electrode active material for electricity storage and electrical storage device 松下电器产业株式会社 2018-05-04 CN disclosed