Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929986 | 0.99 | POLB (0.36) | POLBGAAGFERCA1CA2 | |
| SCHEMBL29355132 | 0.99 | POLB (0.36) | POLBGAAGFERCA1CA2 | |
| SCHEMBL30966657 | 0.97 | POLB (0.35) | POLBGAAGFERCA1CA2 | |
| SCHEMBL29639554 | 0.91 | CA1 (0.38) | CA1CA2CA7CA9CYP2D6 | |
| SCHEMBL28513987 | 0.90 | ALDH1A1 (0.34) | POLBGAAGFERCA1CA2 | |
| SCHEMBL29358193 | 0.89 | CA1 (0.38) | POLBCA1CA2CA7CA9 | |
| SCHEMBL352423 | 0.89 | CA1 (0.38) | POLBCA1CA2CA7CA9 | |
| SCHEMBL12929999 | 0.87 | — | — | |
| SCHEMBL19469294 | 0.86 | CA1 (0.36) | CA1CA2CA7CA9HDAC4 | |
| SCHEMBL21521378 | 0.83 | POLB (0.38) | POLBGAAGFERCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210225-A | Substituted aminoquinolones as immuno-activated DGKALPHA inhibitors | 拜耳公司 | 2022-10-18 | — | — | CN | disclosed |