SCHEMBL352423

SCHEMBL352423

COc1ccc(OC)c(P(C(C)(C)C)C(C)(C)C)c1-c1c(C(C)C)cc(C(C)C)cc1C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
HDAC4 P56524 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TSHR P16473 1/20 0.32
CYP2D6 P10635 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ROCK2 O75116 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
SCN1A P35498 1/20 0.30
SCN2A Q99250 1/20 0.30
SCN3A Q9NY46 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358193 1.00 CA1 (0.38) CA1CA2CA7CA9HDAC4
SCHEMBL29639554 0.99 CA1 (0.38) CA1CA2CA7CA9HDAC4
SCHEMBL19469294 0.96 CA1 (0.36) CA1CA2CA7CA9HDAC4
SCHEMBL12929986 0.91 POLB (0.36) CA1CA2CA7CA9HDAC4
SCHEMBL29355132 0.91 POLB (0.36) CA1CA2CA7CA9HDAC4
SCHEMBL28859005 0.89 POLB (0.35) CA1CA2CA7CA9HDAC4
SCHEMBL30966657 0.89 POLB (0.35) CA1CA2CA7CA9HDAC4
Trifluoromethanesulfonic Acid SCHEMBL30107006 0.88 CA1 (0.36) CA1CA2CA7CA9ALDH1A1
SCHEMBL20346570 0.86 CA1 (0.33) CA1CA2CA7CA9
SCHEMBL28513987 0.82 ALDH1A1 (0.34) CA1CA2CA7CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119731143-A Process for the preparation of biobased olefins from primary alcohols 巴斯夫欧洲公司 2025-03-28 CN claimed
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same YALE UNIVERSITY (US) 2025-02-25 US claimed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 US claimed
US-12162829-B2 Gas phase process for acrylate production from ethylene and carbon dioxide CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-12-10 US claimed
US-12122788-B2 Process of making CFTR modulators VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-10-22 US claimed
US-20240326030-A1 PALLADIUM COMPLEX AND CATALYST EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2024-10-03 US claimed
US-20240300922-A1 PROCESS FOR PREPARING EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION 2024-09-12 US claimed
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same YALE UNIVERSITY (US) 2024-08-27 US claimed
EP-4359401-A1 PROCESS FOR PREPARING EGFR INHIBITORS Blueprint Medicines Corporation (US) 2024-05-01 EP claimed
CN-112469690-B Method for producing arylamines 默克专利有限公司 2024-04-16 CN claimed
CN-108484577-A A kind of pyrimidine-quinolones heterocomplex and its preparation method and application 复旦大学 2018-09-04 CN claimed
EP-2887941-B1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS ABBVIE IRELAND UNLIMITED CO (IE) 2018-07-11 EP claimed
US-20170305948-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2017-10-26 US claimed
EP-3204395-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME Yale University (US) 2017-08-16 EP claimed
EP-2593439-B1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS ABBVIE BAHAMAS LTD (BS) 2016-08-17 EP claimed
WO-2016057600-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME YALE UNIVERSITY (US) 2016-04-14 WO claimed
US-9255074-B2 Process for preparing antiviral compounds ABBVIE INC. (US) 2016-02-09 US claimed
US-9233922-B2 Process for producing N-(hetero)arylazoles TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-01-12 US claimed
US-8895737-B2 Process for preparing antiviral compounds ABBVIE INC. 2014-11-25 US claimed
US-20130224149-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS ABBVIE INC. (US) 2013-08-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130224149-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS HAVCR2, RNASE1, MAVS CA1 4130/4885CA2 4346/4885CA7 3225/4885
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 CA1 44/4885CA2 93/4885CA7 72/4885
US-12162829-B2 Gas phase process for acrylate production from ethylene and carbon dioxide MSMO1, ALOX15, ALOX12 CA1 2190/4885CA2 1121/4885CA7 473/4885
US-20240326030-A1 PALLADIUM COMPLEX AND CATALYST EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME PDCD6IP, PDPK1, PDCD10 CA1 1318/4885CA2 1046/4885CA7 1476/4885
US-20240300922-A1 PROCESS FOR PREPARING EGFR INHIBITORS EGFR, ERBB2, ERBB4 CA1 3166/4885CA2 1258/4885CA7 1032/4885
US-12122788-B2 Process of making CFTR modulators CFTR, SLC26A4, TMEM109 CA1 4856/4885CA2 2605/4885CA7 4060/4885
US-20170305948-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 CA1 44/4885CA2 93/4885CA7 72/4885
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same TET2, TIMCC, MDM4 CA1 21/4885CA2 30/4885CA7 31/4885
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same TIMCC, YAP1, TET2 CA1 44/4885CA2 108/4885CA7 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.