Sugi Predict

Sugi Predict / Compounds / SCHEMBL29358193

SCHEMBL29358193

SCHEMBL29358193

COc1ccc(OC)c(P(C(C)(C)C)C(C)(C)C)c1-c1c(C(C)C)cc(C(C)C)cc1C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ CA7 P43166 1/20 0.38
▸ CA9 Q16790 1/20 0.38
▸ HDAC4 P56524 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.32
▸ TSHR P16473 1/20 0.32
▸ CYP2D6 P10635 1/20 0.31
▸ ADRA2A P08913 1/20 0.31
▸ ADRA1A P35348 1/20 0.31
▸ POLB P06746 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ ROCK2 O75116 1/20 0.30
▸ GABRA1 P14867 1/20 0.30
▸ GABRB2 P47870 1/20 0.30
▸ SCN1A P35498 1/20 0.30
▸ SCN2A Q99250 1/20 0.30
▸ SCN3A Q9NY46 1/20 0.30
▸ MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL352423 1.00 CA1 (0.38) CA1CA2CA7CA9HDAC4
SCHEMBL29639554 0.99 CA1 (0.38) CA1CA2CA7CA9HDAC4
SCHEMBL19469294 0.96 CA1 (0.36) CA1CA2CA7CA9HDAC4
SCHEMBL12929986 0.91 POLB (0.36) CA1CA2CA7CA9HDAC4
SCHEMBL29355132 0.91 POLB (0.36) CA1CA2CA7CA9HDAC4
SCHEMBL28859005 0.89 POLB (0.35) CA1CA2CA7CA9HDAC4
SCHEMBL30966657 0.89 POLB (0.35) CA1CA2CA7CA9HDAC4
Trifluoromethanesulfonic Acid SCHEMBL30107006 0.88 CA1 (0.36) CA1CA2CA7CA9ALDH1A1
SCHEMBL20346570 0.86 CA1 (0.33) CA1CA2CA7CA9
SCHEMBL28513987 0.82 ALDH1A1 (0.34) CA1CA2CA7CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388564-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS EDGEWISE THERAPEUTICS INC (US) 2025-12-25 — — US claimed
EP-4634171-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE F. Hoffmann-La Roche AG (CH) 2025-10-22 — — EP claimed
US-20250313551-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE HOFFMANN-LA ROCHE INC. (US) 2025-10-09 — — US claimed
US-20250197380-A1 PHARMACEUTICAL INTERMEDIATE AND SYNTHESIS METHOD, AND ISOQUINOLINE DERIVATIVE AND SYNTHESIS METHOD THEREFOR BANGENTAI(SHANDONG) BIOSCIENCES GROUP SHARE CO., LTD. (CN) 2025-06-19 — — US claimed
WO-2025123046-A1 SYNTHESIS OF LEUCINE-RICH REPEAT KINASE 2 MODULATORS ARVINAS OPERATIONS, INC. (US) 2025-06-12 — — WO claimed
CN-120004934-A Preparation method of benzo-silicon-containing octatomic ring compound 郑州大学 2025-05-16 — — CN claimed
EP-4522599-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS EDGEWISE THERAPEUTICS, INC. (US) 2025-03-19 — — EP claimed
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same YALE UNIVERSITY (US) 2025-02-25 — — US claimed
CN-119317621-A Process for preparing pyridazinone compounds 艾知怀斯治疗学公司 2025-01-14 — — CN claimed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 — — US claimed
WO-2022136049-A2 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2022-06-30 — — WO claimed
WO-2022127320-A1 INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 四川大学 2022-06-23 — — WO claimed
CN-114591273-A Synthesis method and application of N-methyl-N' -tetrahydrofuran formyl propane diamine oxalate 邦恩泰(山东)生物医药科技集团股份有限公司 2022-06-07 — — CN claimed
CN-114573569-A Preparation method of isoquinoline compounds 邦恩泰(山东)生物医药科技集团股份有限公司 2022-06-03 — — CN claimed
CN-114573506-A Drug intermediate and synthetic method thereof, isoquinoline derivative and synthetic method thereof 邦恩泰(山东)生物医药科技集团股份有限公司 2022-06-03 — — CN claimed
CN-114560815-A (2- ((5-chloro-substituted phenylaminopyrimidin-2-yl) amino) phenyl) carbamic acid tert-butyl ester derivative 北京工业大学 2022-05-31 — — CN claimed
CN-114507252-A Synthesis method of novel aryl silane compound 广西大学 2022-05-17 — — CN claimed
CN-114502558-A Method for preparing activin receptor-like kinase inhibitors 缆图药品公司 2022-05-13 — — CN claimed
CN-114423764-A Intermediate, preparation method and application thereof 四川大学 2022-04-29 — — CN claimed
CN-113429340-B Method for preparing 4- (6-aminopyridine-3-yl) piperazine-1-carboxylic acid tert-butyl ester 神隆医药（常熟）有限公司 2022-04-19 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 CA1 44/4885CA2 93/4885CA7 72/4885
US-20250388564-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS MUSK, SMN1; SMN2, PAX3 CA1 4405/4885CA2 1536/4885CA7 2083/4885
US-20250197380-A1 PHARMACEUTICAL INTERMEDIATE AND SYNTHESIS METHOD, AND ISOQUINOLINE DERIVATIVE AND SYNTHESIS METHOD THEREFOR PARK7, SQLE, CYP4F11 CA1 3270/4885CA2 4047/4885CA7 2835/4885
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same TET2, TIMCC, MDM4 CA1 21/4885CA2 30/4885CA7 31/4885
US-20250313551-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE NQO2, SDHA, NDUFS3 CA1 3931/4885CA2 3419/4885CA7 2874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.