Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 9/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216508 | 0.89 | L3MBTL1 (0.60) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL25422412 | 0.87 | DYRK1B (0.48) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL30461607 | 0.87 | DYRK1B (0.48) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL15757614 | 0.81 | L3MBTL1 (0.56) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL30460415 | 0.81 | DYRK1A (0.54) | KDM4EHTR6DRD2HTR2AHTR7 | |
| SCHEMBL15757712 | 0.79 | L3MBTL1 (0.53) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL15757304 | 0.79 | L3MBTL1 (0.53) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL15757553 | 0.79 | L3MBTL1 (0.53) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL15757671 | 0.77 | L3MBTL1 (0.51) | L3MBTL1FLT3KDM4EUBE2NHTR6 | |
| SCHEMBL3819496 | 0.77 | HTR6 (0.58) | L3MBTL1FLT3HTR6DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218838-A | Pyrimidine radicals indole derivatives and preparation method thereof and application in preparation of anti-tumor drugs | 青岛海洋生物医药研究院股份有限公司 | 2018-06-29 | — | — | CN | disclosed |