Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 8/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689385 | 1.00 | DNM2 (0.47) | DNM2TLR8SOAT1HCAR3CYP4Z1 | |
| SCHEMBL514929 | 0.98 | TLR8 (0.46) | DNM2TLR8SOAT1HCAR3CYP4Z1 | |
| SCHEMBL1638321 | 0.81 | TLR8 (0.34) | DNM2TLR8SOAT1HCAR3CYP4Z1 | |
| SCHEMBL28163938 | 0.79 | SOAT1 (0.48) | DNM2TLR8SOAT1HCAR3CYP4Z1 | |
| SCHEMBL17927689 | 0.77 | SOAT1 (0.46) | DNM2TLR8SOAT1HCAR3CYP4Z1 | |
| SCHEMBL4099219 | 0.74 | KDM4E (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL23768365 | 0.74 | SOAT1 (0.49) | DNM2TLR8SOAT1HCAR3 | |
| SCHEMBL28468131 | 0.73 | — | — | |
| SCHEMBL23956969 | 0.72 | SOAT1 (0.48) | DNM2TLR8SOAT1HCAR3CYP4Z1 | |
| SCHEMBL13356938 | 0.71 | TLR8 (0.47) | TLR8SOAT1HCAR3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107857738-A | The synthesis and application of hexadecylamino pyrrolotriazine derivatives | 贺州学院 | 2018-03-30 | — | — | CN | disclosed |