Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | DNM2 | P50570 | 11/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294339 | 0.85 | HCAR3 (0.42) | SOAT1HCAR3TLR8 | |
| SCHEMBL23956969 | 0.81 | SOAT1 (0.48) | SOAT1HCAR3DNM2TLR8 | |
| SCHEMBL8046837 | 0.80 | HRH3 (0.45) | TLR8 | |
| SCHEMBL12895618 | 0.77 | HCAR3 (0.39) | HCAR3 | |
| SCHEMBL12691774 | 0.76 | NPC1 (0.68) | SOAT1 | |
| SCHEMBL1752801 | 0.76 | SYK (0.41) | — | |
| SCHEMBL20037454 | 0.76 | IL1B (0.45) | — | |
| SCHEMBL18913398 | 0.74 | DNM2 (0.47) | SOAT1DNM2TLR8 | |
| SCHEMBL22265370 | 0.74 | HCAR3 (0.59) | SOAT1HCAR3DNM2TLR8 | |
| SCHEMBL28859627 | 0.74 | DNM2 (0.47) | SOAT1HCAR3DNM2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253554-A1 | SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253554-A1 | SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS | TYK2, JAK3, JAK2 | SOAT1 4138/4885HCAR3 1016/4885DNM2 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.