SCHEMBL28859640

SCHEMBL28859640

CCCCC[n+]1ccccc1.CS(=O)(=O)[O-]

nearest known ligand 0.70

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A known ✓ P08913 2/20 0.70
CHRM1 known ✓ P11229 2/20 0.70
SLC6A2 known ✓ P23975 2/20 0.70
SLC6A4 known ✓ P31645 2/20 0.70
SLC6A3 known ✓ Q01959 2/20 0.70
HTR1A known ✓ P08908 1/20 0.70
DRD1 known ✓ P21728 1/20 0.70
ADRA1A known ✓ P35348 1/20 0.70
DRD3 known ✓ P35462 1/20 0.70
EGFR known ✓ P00533 1/20 0.68
ADRA2B known ✓ P18089 1/20 0.68
ADRA2C known ✓ P18825 1/20 0.68
HTR2A known ✓ P28223 1/20 0.68
HTR2C known ✓ P28335 1/20 0.68
ACHE P22303 4/20 0.70
CHRM2 P08172 2/20 0.70
ADORA3 P0DMS8 2/20 0.70
ABCB11 O95342 1/20 0.70
ESR1 P03372 1/20 0.70
PGR P06401 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30212763 0.98 ACHE (0.74) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL29252400 0.98 ACHE (0.74) ACHECHRM2ADRA2AADORA3CHRM1
Cetylpyridinium SCHEMBL11862206 0.98 ACHE (0.74) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL29252690 0.98 ACHE (0.74) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL11870741 0.98 ACHE (0.74) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL29252196 0.98 ACHE (0.74) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL29251688 0.98 ACHE (0.74) ACHECHRM2ADRA2AADORA3CHRM1
SCHEMBL1715389 0.94 ACHE (0.61) ACHECHRM2ADRA2AADORA3CHRM1
Sulfuric Acid SCHEMBL9784616 0.92 ACHE (0.77) ACHECHRM2ADRA2AADORA3CHRM1
Sulfuric Acid SCHEMBL11121738 0.92 ACHE (0.77) ACHECHRM2ADRA2AADORA3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117999475-A Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2024-05-07 CN disclosed
WO-2023046704-A1 ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR Dräger Safety AG & Co. KGaA (DE) 2023-03-30 WO disclosed
CN-107532129-B Efficient small volume nucleic acid synthesis 生命技术公司 2022-09-13 CN disclosed