SCHEMBL28859704

SCHEMBL28859704

Clc1cccc(CC2CO2)c1CC1CO1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.37
CYP2A13 Q16696 3/20 0.36
HTT P42858 3/20 0.36
GLA P06280 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PNMT P11086 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
KMT2A Q03164 1/20 0.34
AKR1B1 P15121 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1907932 0.86 TAAR1 (0.35) TAAR1CYP2A13HTTGLANPSR1
SCHEMBL2778676 0.86 ALDH1A1 (0.39) GLAALDH1A1TP53CYP3A4TSHR
SCHEMBL3534749 0.82 TAAR1 (0.51) TAAR1CYP2A13HTTPNMTALDH1A1
SCHEMBL31076452 0.80 TAAR1 (0.36) TAAR1CYP2A13HTTPNMTALDH1A1
SCHEMBL13116361 0.80 HSP90AA1 (0.45) TAAR1CYP2A13PNMTALDH1A1TP53
SCHEMBL1944225 0.80 TAAR1 (0.50) TAAR1CYP2A13HTTNPSR1ALDH1A1
Ammonia Solution, Strong SCHEMBL1411992 0.79 ALDH1A1 (0.35) GLAALDH1A1TP53CYP3A4TSHR
SCHEMBL3117388 0.79 ALDH1A1 (0.41) TAAR1CYP2A13GLAALDH1A1TP53
SCHEMBL9471583 0.78 ALDH1A1 (0.34) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL21359692 0.78 PNMT (0.35) PNMTALDH1A1TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104903359-B Method for forming polymerization catalysts with controlled catalyst properties and use thereof in olefin polymerization 格雷斯公司 2018-05-08 CN disclosed