Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502048 | 0.86 | HDAC6 (0.42) | CA12CA6CA7CA9CA14 | |
| SCHEMBL28659907 | 0.85 | PAOX (0.45) | CA12CA6CA7CA9CA14 | |
| SCHEMBL28137724 | 0.84 | KDM4E (0.37) | MEN1KMT2AACHEALDH1A1LMNA | |
| SCHEMBL2704670 | 0.83 | EPHX1 (0.37) | CA12CA9ACHECA2CA1 | |
| SCHEMBL27872670 | 0.83 | ACHE (0.38) | ACHE | |
| SCHEMBL2703359 | 0.83 | ALDH1A1 (0.33) | ACHEALDH1A1LMNAALOX15 | |
| SCHEMBL1205899 | 0.81 | EPHX1 (0.40) | CA12CA9ACHECA2CA1 | |
| Methane SCHEMBL27985713 | 0.81 | ALDH1A1 (0.33) | ACHEALDH1A1LMNAALOX15 | |
| Hydrochloric Acid SCHEMBL27716907 | 0.81 | ALDH1A1 (0.33) | ACHEALDH1A1LMNAALOX15KDM4E | |
| SCHEMBL27684736 | 0.80 | EPHX1 (0.43) | CA12CA9ACHECA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-A | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2018-06-08 | — | — | CN | disclosed |