Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872670 | 0.85 | ACHE (0.38) | ACHE | |
| SCHEMBL12535592 | 0.84 | TSHR (0.38) | TSHRACHESMN1; SMN2LMNA | |
| SCHEMBL28860189 | 0.84 | CA12 (0.36) | KDM4EALDH1A1MEN1KMT2AACHE | |
| SCHEMBL27645900 | 0.81 | CYP2C9 (0.37) | KDM4EALDH1A1MAPTACHESMN1; SMN2 | |
| SCHEMBL27880456 | 0.79 | ABCB11 (0.36) | ALDH1A1TSHRACHE | |
| SCHEMBL29308970 | 0.79 | ABCB11 (0.36) | ALDH1A1TSHRACHE | |
| SCHEMBL27766308 | 0.79 | ACHE (0.35) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL28244485 | 0.79 | GAA (0.37) | KDM4EALDH1A1ACHE | |
| SCHEMBL28758495 | 0.78 | PAOX (0.36) | KDM4EMEN1KMT2AACHESMN1; SMN2 | |
| SCHEMBL27993979 | 0.77 | SAT1 (0.41) | MEN1KMT2AATMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981470-B | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | 拜耳制药股份公司 | 2017-04-19 | — | — | CN | disclosed |