Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268272 | 0.82 | CYP1A2 (0.40) | GAAMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL27684708 | 0.79 | HTR1A (0.47) | HTR1ADRD2GAAABCB1MAPT | |
| SCHEMBL28317762 | 0.79 | TSHR (0.48) | HTR1ADRD2GAAABCB1MAPT | |
| SCHEMBL7243289 | 0.79 | HTR1A (0.47) | HTR1ADRD2GAAPTGER1PTGER4 | |
| SCHEMBL1616224 | 0.77 | MAPT (0.55) | HTR1ADRD2GAAMAPTMAPK1 | |
| SCHEMBL27934804 | 0.77 | HTR1A (0.49) | HTR1AGAAMAPTMAPK1TDP1 | |
| SCHEMBL724160 | 0.76 | HTR1A (0.39) | HTR1ADRD2GAAPTGER1PTGER4 | |
| SCHEMBL183414 | 0.76 | MAPT (0.48) | HTR1ADRD2GAAMAPTMAPK1 | |
| SCHEMBL10956404 | 0.76 | HTR1A (0.65) | HTR1ADRD2GAAPTGER1PTGER4 | |
| SCHEMBL28375679 | 0.76 | HTR1A (0.65) | HTR1ADRD2GAAPTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026077-A | PHENOXYMETHYL DERIVATIVES | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | disclosed |