Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28317762 | 0.84 | TSHR (0.48) | HTR1ADRD2LMNALIPEMAPT | |
| SCHEMBL27684708 | 0.84 | HTR1A (0.47) | HTR1ADRD2LMNALIPEMAPT | |
| SCHEMBL183414 | 0.81 | MAPT (0.48) | HTR1ADRD2LMNALIPEMAPT | |
| SCHEMBL6996715 | 0.80 | APP (0.47) | HTR1ADRD2LMNALIPEMAPT | |
| SCHEMBL692555 | 0.79 | HTR1A (0.67) | HTR1ADRD2ELANEF2LMNA | |
| SCHEMBL28860396 | 0.79 | HTR1A (0.46) | HTR1ADRD2LIPEMAPTTDP1 | |
| SCHEMBL1616224 | 0.78 | MAPT (0.55) | HTR1ADRD2LIPEMAPTTDP1 | |
| SCHEMBL5315646 | 0.77 | APP (0.47) | HTR1ADRD2LIPEMAPTTDP1 | |
| SCHEMBL1099955 | 0.77 | MAPT (0.44) | HTR1ADRD2LIPEMAPTTDP1 | |
| SCHEMBL7003209 | 0.77 | APP (0.47) | HTR1ADRD2LMNALIPEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522631-B | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the ss2 adrenergic receptor | ALMIRALL LAB | 2013-06-12 | — | — | CN | disclosed |
| CN-101218203-B | Fluorinated derivatives of 4- (2-amino-1-hydroxyethyl) phenol as beta 2 adrenoreceptor agonists | ALMIRALL SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101522631-A | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the ss2 adrenergic receptor | ALMIRALL LAB (ES) | 2009-09-02 | — | — | CN | disclosed |
| CN-101218203-A | Derivatives of 4-(2-amino-1-hydroxyethyl) phenol as agonists of the ss2 adrenergic receptor | ALMIRALL PRODESFARMA SA (ES) | 2008-07-09 | — | — | CN | disclosed |
| US-20030045727-A1 | Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-03-06 | — | — | US | disclosed |
| EP-1254885-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE SECONDARY ALCOHOLS HAVING NITROGENOUS OR OXYGENIC FUNCTIONAL GROUPS | Asahi Kasei Kabushiki Kaisha (JP) | 2002-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045727-A1 | Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups | ADH1A, ADH5, ADH1C | HTR1A 2261/4885DRD2 41/4885ELANE 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.