SCHEMBL28860722

SCHEMBL28860722

O=C(O)C(CCc1ccc(OCc2ccccc2)cc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.64
FFAR4 Q5NUL3 3/20 0.64
PPARG P37231 3/20 0.60
PPARA Q07869 3/20 0.60
MMP12 P39900 1/20 0.59
AKR1B1 P15121 1/20 0.54
PPARD Q03181 1/20 0.54
LTA4H P09960 2/20 0.54
EPHX2 P34913 1/20 0.54
LAP3 P28838 1/20 0.53
CYP1A2 P05177 1/20 0.53
MMP2 P08253 1/20 0.53
MMP3 P08254 1/20 0.53
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
CPA3 P15088 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28224291 1.00 FFAR1 (0.64) FFAR1FFAR4PPARGPPARAMMP12
SCHEMBL6716210 0.92 FFAR1 (0.61) FFAR1FFAR4PPARGPPARAMMP12
SCHEMBL1856449 0.87 LTA4H (0.60) FFAR1FFAR4PPARGPPARAMMP12
SCHEMBL6716294 0.87 PPARA (0.60) FFAR1FFAR4PPARGPPARAPPARD
SCHEMBL27439147 0.86 LTA4H (0.58) FFAR1FFAR4PPARGPPARAMMP12
SCHEMBL27439146 0.86 LTA4H (0.58) FFAR1FFAR4PPARGPPARAMMP12
SCHEMBL8000823 0.85 PPARG (0.63) FFAR1FFAR4PPARGPPARAPPARD
SCHEMBL5727650 0.85 FFAR1 (0.52) FFAR1FFAR4PPARGPPARALAP3
SCHEMBL6939260 0.85 PPARG (0.61) FFAR1FFAR4PPARGPPARAPPARD
SCHEMBL7632753 0.85 PPARG (0.61) FFAR1FFAR4PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669423-B The novel synthesis of two kinds of enantiomters of 4- (4- (benzyloxy) phenyl) -2- hydroxybutyric acids 江西科技师范大学 2018-06-29 CN disclosed