Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27439146 | 1.00 | LTA4H (0.58) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL1856449 | 0.96 | LTA4H (0.60) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL22367637 | 0.90 | MMP2 (0.63) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL29779565 | 0.90 | MMP2 (0.63) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL1859995 | 0.89 | LTA4H (0.52) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL6716210 | 0.86 | FFAR1 (0.61) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL28860722 | 0.86 | FFAR1 (0.64) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL28224291 | 0.86 | FFAR1 (0.64) | LTA4HEPHX2FFAR1FFAR4MMP12 | |
| SCHEMBL1862995 | 0.85 | GRIK1 (0.61) | MMP2MMP3 | |
| SCHEMBL1856424 | 0.84 | GPR132 (0.54) | LTA4HEPHX2MMP12MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053607-A | The human immunity that is used for the treatment of AIDS lacks the inhibitor of virus protease | MERCK & CO INC (US) | 1991-08-07 | — | — | CN | disclosed |