Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | PPARA | Q07869 | 4/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860722 | 0.92 | FFAR1 (0.64) | FFAR1FFAR4LTA4HEPHX2PPARG | |
| SCHEMBL28224291 | 0.92 | FFAR1 (0.64) | FFAR1FFAR4LTA4HEPHX2PPARG | |
| SCHEMBL1856449 | 0.90 | LTA4H (0.60) | FFAR1FFAR4LTA4HEPHX2PPARG | |
| SCHEMBL7632753 | 0.88 | PPARG (0.61) | FFAR1FFAR4LTA4HPPARGPPARA | |
| SCHEMBL6939260 | 0.88 | PPARG (0.61) | FFAR1FFAR4LTA4HPPARGPPARA | |
| SCHEMBL27439147 | 0.86 | LTA4H (0.58) | FFAR1FFAR4LTA4HEPHX2PPARG | |
| SCHEMBL27439146 | 0.86 | LTA4H (0.58) | FFAR1FFAR4LTA4HEPHX2PPARG | |
| SCHEMBL6713184 | 0.86 | LMNA (0.57) | FFAR1FFAR4LTA4HEPHX2PPARG | |
| SCHEMBL5727666 | 0.86 | PPARG (0.56) | FFAR1PPARGPPARAFOLH1ALOX5 | |
| SCHEMBL5331355 | 0.86 | CTRC (0.59) | PPARGPPARAFOLH1ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| CN-1280561-A | Amidocarboxylic acid derivatives | SANKYO CO (JP) | 2001-01-17 | — | — | CN | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | FFAR1 39/4885FFAR4 123/4885LTA4H 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.