Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860731 | 0.84 | ESR1 (0.35) | CNR2KLF10CYP4F2CYP4A11ABCB11 | |
| SCHEMBL28160417 | 0.77 | CNR2 (0.57) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL15630699 | 0.76 | RORC (0.51) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL10228098 | 0.76 | CNR2 (0.51) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL4624085 | 0.75 | KLF10 (0.47) | PLGKLF10CYP1A2MAOB | |
| SCHEMBL22992388 | 0.75 | CNR2 (0.48) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL30546502 | 0.75 | CNR2 (0.48) | CNR2F2F10PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL15609606 | 0.75 | RORC (0.50) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL28160919 | 0.74 | CNR2 (0.59) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL27775464 | 0.74 | CNR2 (0.45) | CNR2F2F10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108112251-A | NRF2 conditioning agents | 葛兰素史克知识产权发展有限公司 | 2018-06-01 | — | — | CN | disclosed |