SCHEMBL28860744

SCHEMBL28860744

CCc1ccc(N=O)c(O)c1O

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 3/20 0.34
ESR2 Q92731 3/20 0.34
FEN1 P39748 1/20 0.32
PRKCI P41743 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3285467 0.81 GABRA1 (0.64) GABRA1GABRB2ALDH1A1LMNA
SCHEMBL45861 0.81 GABRA1 (0.68) GABRA1GABRB2ESR1ESR2FEN1
SCHEMBL3087121 0.81 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1MAPTXBP1
SCHEMBL4652293 0.72 MEN1 (0.40) GABRA1GABRB2ALDH1A1LMNAESR1
SCHEMBL3078639 0.72 MAPT (0.42) ALDH1A1KDM4ENPC1MAPTXBP1
SCHEMBL2475390 0.72 GABRA1 (0.56) GABRA1GABRB2ESR1ESR2PRKCI
SCHEMBL29719025 0.72 GABRA1 (0.56) GABRA1GABRB2ESR1ESR2PRKCI
SCHEMBL20861837 0.71 HSP90AA1 (0.39) ALDH1A1LMNAKDM4ENPC1MAPT
SCHEMBL5196215 0.70 PRKCI (0.57) GABRA1GABRB2ESR1ESR2PRKCI
SCHEMBL5676415 0.70 GABRA1 (0.54) GABRA1GABRB2ALDH1A1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108191683-A Method for preparing N, N-dihydroxyethyl-4-nitrosoaniline in pipeline manner 浙江鼎龙科技有限公司 2018-06-22 CN claimed