Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317303 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL6781180 | 0.84 | CYP19A1 (0.46) | ALDH1A1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL28226006 | 0.82 | CYP19A1 (0.41) | ALDH1A1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL31121835 | 0.80 | CTRC (0.47) | ALDH1A1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL5856736 | 0.79 | KDM4E (0.47) | ALDH1A1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL8274960 | 0.78 | CTRC (0.61) | ALDH1A1KMT2ASIRT2ALDH2CTRC | |
| SCHEMBL576832 | 0.78 | CTRC (0.61) | ALDH1A1KMT2ASIRT2ALDH2CTRC | |
| SCHEMBL10690037 | 0.76 | SIRT2 (0.56) | ALDH1A1MEN1KMT2ASIRT2CYP19A1 | |
| SCHEMBL28226010 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1MAPK1KMT2A | |
| SCHEMBL10017610 | 0.76 | CTRC (0.47) | ALDH1A1MEN1KMT2ASIRT2ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250128-A | Compound as potassium channel modulating agents | 江苏先声药业有限公司 | 2018-07-06 | — | — | CN | disclosed |